Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia a Placebo Controlled Clinical Trial
试验速览
- 阶段
- 早期 1 期
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Changes in Semen analysis parameters compared to baseline
研究概览
简要总结
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
详细描述
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia a placebo controlled clinical trial
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •of in¬fertility of 1 year or more without the use of contraception
排除标准
- •o Active genital infections.
- •Patients with ejaculatory dysfunction
- •Azoospermia
研究组 & 干预措施
Group 1
will receive a daily dose of 200 mg of CoQ10 for 3 months
干预措施: co enzyme Q10 , L- Carnitine (Drug)
Group 2
will receive L-carnitine 1 tablet per day orally for 3 months
干预措施: co enzyme Q10 , L- Carnitine (Drug)
Group 3
will receive combination of a daily dose of 200 mg of CoQ10 and 1 tablet of L-carnitine for 3 months
干预措施: co enzyme Q10 , L- Carnitine (Drug)
Group 4
will receive a placebo for 3 months
干预措施: co enzyme Q10 , L- Carnitine (Drug)
结局指标
主要结局
Changes in Semen analysis parameters compared to baseline
时间窗: 6 months
Changes in Semen analysis parameters compared to baseline
次要结局
- Serum hormone levels ([FSH], [LH], testosterone, and prolactin) levels compared to baseline and Cost analysis(6 moths)