Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Early Phase 1
Recruiting
- Conditions
- OligospermiaInfertility Unexplained
- Interventions
- Registration Number
- NCT06342856
- Lead Sponsor
- Ain Shams University
- Brief Summary
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
- Detailed Description
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia a placebo controlled clinical trial
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Male
- Target Recruitment
- 120
Inclusion Criteria
- of in¬fertility of 1 year or more without the use of contraception
Exclusion Criteria
-
o Active genital infections.
- Patients with ejaculatory dysfunction
- Azoospermia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Group 1 co enzyme Q10 , L- Carnitine will receive a daily dose of 200 mg of CoQ10 for 3 months Group 2 co enzyme Q10 , L- Carnitine will receive L-carnitine 1 tablet per day orally for 3 months Group 3 co enzyme Q10 , L- Carnitine will receive combination of a daily dose of 200 mg of CoQ10 and 1 tablet of L-carnitine for 3 months Group 4 co enzyme Q10 , L- Carnitine will receive a placebo for 3 months
- Primary Outcome Measures
Name Time Method Changes in Semen analysis parameters compared to baseline 6 months Changes in Semen analysis parameters compared to baseline
- Secondary Outcome Measures
Name Time Method Serum hormone levels ([FSH], [LH], testosterone, and prolactin) levels compared to baseline and Cost analysis 6 moths Serum hormone levels (\[FSH\], \[LH\], testosterone, and prolactin) levels compared to baseline and Cost analysis
Trial Locations
- Locations (1)
Ain Shams University
🇪🇬Cairo, Egypt