Multi-unit microneurography and modeling of afferent responses of human muscle mechanorecpetors

Withdrawn

• Conditions: fysiologie of diagnostiek van de functie van mechanoreceptoren in spieren; function of mechanoreceptors; function of muscle spindles and Golgi tendon organs; 10029317

• Registration Number: NL-OMON30370
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

healthy volunteers
using no medication
age 18 - 40 years

Exclusion Criteria

microneurographic examination of nervus radialis of same arm in previous month
history of movement disorders in the arms

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome of this study is the time required for finding a useful<br /><br>electrode position (evaluating two search methods), the measurement time until<br /><br>signal loss and a variety of indicators for the (relative) presence of the<br /><br>different fiber types in the signal, and furthermore the optimized settings of<br /><br>filters and other signal analysis techniques.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary output parameters are diverse quantitative (model) descriptions of<br /><br>the mechanoreceptor functions, like the effect of amplitude and frequency of<br /><br>the movements. For completeness, we will also record any after effects of the<br /><br>microneurography as observed by the subjects.</p><br>