Multi-unit microneurography and modeling of afferent responses of human muscle mechanoreceptors

Completed

• Conditions: fysiologie of diagnostiek van de functie van mechanoreceptoren in spieren; function of muscle spindles and Golgi tendon organs; function of mechanoreceptors; 10029317

• Registration Number: NL-OMON35175
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 14

Inclusion Criteria

healthy volunteers
using no medication
age at least 18 years

Exclusion Criteria

microneurographic examination of nervus radialis of same arm in previous month
history of movement disorders in the arms

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcomes of this study are the time required for finding a useful<br /><br>electrode position, the measurement duration until signal loss, a variety of<br /><br>indicators for the (relative) presence of the different fiber types in the<br /><br>signal, the signal-to-noise ratio and the test reproducibility.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary output parameters are diverse quantitative (model) descriptions of<br /><br>the mechanoreceptor functions, like the effect of amplitude and frequency of<br /><br>the movements, and the optimized settings of filters and other signal analysis<br /><br>techniques.</p><br>