Antioxidant effect of carqueja infusion in climacteric wome

Not Applicable

• Conditions: Oxidative stress; menopause.; G08.686.157.500; G03.673

• Registration Number: RBR-3h2xcn
• Lead Sponsor: niversidade Regional do Noroeste do Estado do Rio Grande do Sul

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women will be included who accept to participate in the research through the signing of the Free and Informed Consent Form, TCLE. Adhere for three months to treatment with Baccharis trimera infusion. Perform all stages of research protocol evaluations.

Exclusion Criteria

Women will be excluded the following drug classes are in continuous use: Hormone Replacement Therapy, HRT or who have previously had this treatment; vitamin supplement, medications for HAS, DM. Women who use medicinal plants on an ongoing basis;Women with low acceptability of Baccharis trimera infusion; Women who participated in the last 6 months of research with herbs, herbal medicines and functional foods.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antioxidant effect: will be checked through levels of substances reactive to thiobarbituric acid, carbonylated proteins, reduced glutathione, the activity of superoxide dismutase and catalase enzymes.

Secondary Outcome Measures

Name	Time	Method
The verification of pressure levels will be performed using an aneroid sphygmomanometer with stethoscope<br>Anthropometric evaluation, through the measurement of weight, height, waist circumference and body fat percentage verification, will also be used to calculate the Body Mass Index (BMI).<br>;Assessment of renal function through urea and creatinine analysis<br>Analysis of hepatic function through the enzymes glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase and gamma glutamyl transferase;Definition of the climacteric phase through the dosage of 17?-estradiol levels<br>Lipid profile through analysis of total cholesterol, High Density Lipoprotein triglycerides<br>Analysis of blood parameters will be performed through the blood count<br><br>;Analysis of blood parameters will be performed through the blood count<br>Fasting glucose analysis