Role of omega- 3 fatty acids in the treatment of periodontal diseases
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/12/047945
- Lead Sponsor
- DR DEVISREE RV
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
i.Periodontally healthy individuals, patients with generalized gingivitis as well as generalized periodontitis diagnosed according to criteria given by American Academy of Periodontology 2017 classification15.
ii.Patients belonging to both sexes who are willing to participate in the study.
I.Pregnant and lactating females
II.Periodontal or orthodontic treatment at least 6 months before the start of the study
III.SRP as part of initial periodontal therapy within the past 6 months
IV.smokers, history of diabetes, radiation therapy, chemotherapy or patients on corticosteroid therapy.
V.any diseases or disorders that compromise wound healing,
VI.any history of chronic inflammatory disease and any oral mucosal inflammatory condition (e.g., aphthous, lichen planus);
VII.Use of antibiotics, corticosteroids and antiâ??inflammatory drugs within 3 months before sampling.
VIII.Patients on regular use of any nutritional supplements which can affect the study outcome
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢% Reduction in number of periodontal pockets with PPD â?¥ 4mm with bleeding on probing in group treated with adjunctive use of omega 3 PUFA and nonsurgical periodontal therapy alone. <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: 0,3,6 months <br/ ><br>
- Secondary Outcome Measures
Name Time Method salivary levels of lipoxin A4 measured using ELISA in group treated with adjunctive use of omega 3 PUFA and nonsurgical periodontal therapy aloneTimepoint: 0,6 months