Graduated compression stockings versus low-molecular-weight heparin for prevention of venous thromboembolism after knee arthroscopy: a prospective randomised trial

niversity Hospital of Padua (Italy)0 个研究点目标入组 1,300 人开始时间: 2007年1月22日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•All consecutive outpatients scheduled for diagnostic arthroscopy or arthroscopy-assisted knee surgery for anterior cruciate ligament reconstruction, partial lateral and/or medial meniscectomy, cartilage shaving or resurfacing, chondroplasty, combined surgical procedures and other surgical procedures (e.g. loose body removal, patella realignment, etc.)

•1. Aged less than 18 years
•2. Pregnancy
•3. Previous deep vein thrombosis (DVT) and/or pulmonary embolism (PE)
•4. Active malignancy
•5. Known thrombophilia
•6. Mandatory anticoagulation
•7. Hypersensitivity to low-molecular weight heparins
•8. History of recent major bleeding, as described below (less than 4 weeks)
•9. Severe renal or hepatic failure
•10. Anticipated poor compliance with the study requirements
•11. Geographic inaccessibility
•Owing to the recommendations of latest ACCP conference, 17 patients with complicated procedures and a tourniquet thigh time longer than 60 minutes were excluded, because they were considered, hypothetically, at higher risk of developing venous thromboembolic complications and pharmacological thromboprophylaxis with fixed-dose of low-molecular weight heparins is suggested (grade 2B).

发起方

niversity Hospital of Padua (Italy)