The effect of N-acetylcysteine ??on myocardial stress in coronary artery bypass surgery
Phase 3
Recruiting
- Conditions
- I25.1???? ???????? ????????? ???.Atherosclerotic heart disease of native coronary artery
- Registration Number
- IRCT20230218057443N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Patients candidates for CABG surgery
informed consent
age (40-70) years
ejection fraction EF = 50%)
non-emergency patients, patients with stable hemodynamics
patients who did not use ECMO and balloon pump before surgery
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Troponin. Timepoint: Before surgery, immediately and eight hours after surgery. Method of measurement: Venous blood sample.;CRP. Timepoint: Before surgery, immediately and 24 hours after surgery. Method of measurement: Venous blood sample.
- Secondary Outcome Measures
Name Time Method Duration of stay in ICU. Timepoint: Time of discharge from ICU. Method of measurement: patient file.;Need for defibrillator shock during surgery. Timepoint: during surgery. Method of measurement: view.;The need for a pacemaker during surgery. Timepoint: during surgery. Method of measurement: view.