The effect of plasma rich in growth factors in treatment of gingival recessio

Phase 2

• Conditions: Gingival Recession.; Gingival recession (generalized)(localized)(post infective)(post-operative)

• Registration Number: IRCT201201168747N1
• Lead Sponsor: Vice chancellor for research, Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

Inclusion criteria : 1) The presence of either bilateral isolated or multiple facial defects with recession depths =2 mm when measured from the cementoenamel junction at anterior teeth or premolars; 2) The defects that are judged as Miller Class I or Class II; 3) The selected teeth should be vital, free of restorations or had restorations removed, and with no bleeding upon probing; 4)The age of patients should be within 18 to 65 5) Good oral hygiene (O´Leary plaque score =%20 ); 6)Width of keratinized gingiva should be <2 mm; 7) Gingival thickness should be >0.5mm. Exclusion criteria: 1) Smoking; 2) Any uncontrolled local or systemic disease that might contraindicate periodontal surgery; 3) Pregnancy; 4) Hematologic disorders; 5) Usage of the drugs that have intervention with wound healing (corticosteroid, chemotherapeutic agents); 6) Usage of the drugs that have intervention with platelet aggregation; 7) Allergy to tetracycline; 8) Traumatic methods of tooth brushing; 9) Applying abrasive dentifrices; 10) Applying removable partial denture; 11) The history of periodontal surgery at the selected site.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gingival recession. Timepoint: Six month after surgery. Method of measurement: Clinical examination.

Secondary Outcome Measures

Name	Time	Method
Width of keratinized gingiva. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Clinical attachment level. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Clinical probing depth. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Vertical depth of gingival recession. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Width of gingival recession. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Gingival thickness. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;Gingival index. Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.;The distance between mucogingival junction and cementoenamel junction (Mgjl). Timepoint: Baseline, 1 and 6 month after surgery. Method of measurement: Clinical examination.