Comparison of intubation rate between High flow nasal cannula versus Non -invasive positive pressure ventilation in acute hypoxic respiratory failure among immunocompromised patients in Emergency department
Phase 3
Recruiting
- Conditions
- Can High flow nasal cannula decrease Intubation rate than Non-invasive positive pressure ventilation in Acute Hypoxemic Respiratory Failure Among Immunocompromised Patientshypoxic respiratory failureimmunocompromisedhigh flow cannulanon invasive positive pressure ventilation
- Registration Number
- TCTR20200309002
- Lead Sponsor
- Ramathibodi hospital Mahidol university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
Age more than 18 year and
Define to Immunocompromised patient at least one; Hematologic malignancy, Solid tumor, HIV, Steroid used (>0.3mg/kg/day > 1month), chemotherapy, Immunosuppressive and
Define to hypoxic respiratory failure; respiratory rate > 24 /min and pulse oximetry< 92% during oxygen cannula 4 LPM or Po2/Fio2< 300 or SatO2/Fio2<255
Exclusion Criteria
1)COPD
2)Asthma
3)Congestive Heart Failure
4)PaCO2 >45 mmHg
5)Systolic Blood Pressure <90 mm Hg or Mean Arterial Blood pressure <65 mmHg
6)Glasgow coma scale <12
7)Circulatory shock or Receiving vasopressor
8)Met indication for Emergency intubation
9)Do not resuscitation Assign before
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method