HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH
Not Applicable
Completed
- Conditions
- BPH With Urinary ObstructionMale
- Registration Number
- NCT04935151
- Lead Sponsor
- Cairo University
- Brief Summary
To compare bipolar resection versus holmium laser enucleation for management of symptomatic large BPH (\> 80 gm)
- Detailed Description
To compare safety and efficacy of bipolar resection (BPRP) versus holmium laser enucleation (HoLEP) for management of symptomatic large BPH (\> 80 gm)
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 112
Inclusion Criteria
- Patients suffering from LUTS secondary to infravesical obstruction from BPH with failed medical treatment
- International Prostate Symptom Score (IPSS) > 13
- a peak urinary flow rate (Qmax) < 15 ml/sec
- a prostate size ≥ 80 gm
Exclusion Criteria
- presence of a urethral stricture
- neurological disorder
- bladder cancer
- prostate cancer
- previous history of bladder neck surgery or TURP
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method hemoglobin drop postoperatively (gm/dL) within two hours after surgery change in hemoglobin concentration postoperatively vs preoperatively
- Secondary Outcome Measures
Name Time Method operative duration in minutes Time lapsed during surgery operative duration
Hospital stay From time of randomisation up to last day of admission in hospital (in days) up to 30 days Hospitalisation starting from day of surgery till the day of discharge from Hospital in days
blood transfusion during surgery and hospitalisation up to 10 days rate of blood transfusion
Trial Locations
- Locations (2)
Cairo University Hospitals
🇪🇬Cairo, Egypt
Theodor Bilharz research institute
🇪🇬Giza, Egypt
Cairo University Hospitals🇪🇬Cairo, Egypt