Perioperative Acute Kidney Injury in Patients With Cystic Fibrosis Undergoing Lung Transplantation: a Retrospective Analysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cystic Fibrosis
- Sponsor
- Policlinico Hospital
- Enrollment
- 85
- Locations
- 1
- Primary Endpoint
- Acute Kidney Injury
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
With this retrospective observational cohort study, we performed a longitudinal assessment of the renal function of the adult CF patients who underwent LUTX, aiming 1) to describe possible risk factors associated with perioperative AKI and 2) to describe AKI short and long term effects on clinical outcomes.
Detailed Description
This study is a retrospective analysis of prospectively collected data from medical records of all consecutive CF patients who underwent LUTX at our Institution from January 2013 to December 2018.
Investigators
Giacomo Grasselli
Professor
Policlinico Hospital
Eligibility Criteria
Inclusion Criteria
- •All patients with CF who underwent LUTX during the study period were considered.
Exclusion Criteria
- •single LUTX
- •re-transplantation
- •missing medical records;
- •age \< 18 years old
Outcomes
Primary Outcomes
Acute Kidney Injury
Time Frame: 1 month
AKI stage 1, stage 2, and stage 3 whether a 1.5-1.9 times, 2-2.9 times, and \>3 times increase from the preoperative creatinine was measured, respectively. Following KIDGO criteria
Secondary Outcomes
- Survival(Until May 31 2021)