Perioperative Acute Kidney Injury in Patients With Cystic Fibrosis Undergoing Lung Transplantation: a Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 85
- 试验地点
- 1
- 主要终点
- Acute Kidney Injury
研究概览
简要总结
With this retrospective observational cohort study, we performed a longitudinal assessment of the renal function of the adult CF patients who underwent LUTX, aiming 1) to describe possible risk factors associated with perioperative AKI and 2) to describe AKI short and long term effects on clinical outcomes.
详细描述
This study is a retrospective analysis of prospectively collected data from medical records of all consecutive CF patients who underwent LUTX at our Institution from January 2013 to December 2018.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with CF who underwent LUTX during the study period were considered.
排除标准
- •single LUTX
- •re-transplantation
- •missing medical records;
- •age < 18 years old
结局指标
主要结局
Acute Kidney Injury
时间窗: 1 month
AKI stage 1, stage 2, and stage 3 whether a 1.5-1.9 times, 2-2.9 times, and \>3 times increase from the preoperative creatinine was measured, respectively. Following KIDGO criteria
次要结局
- Survival(Until May 31 2021)
研究者
Giacomo Grasselli
Professor
Policlinico Hospital