Effect of crocin supplementation in patients with diabetic nephropathy

Phase 3

Recruiting

Conditions: Diabetic nephropathy.
Diabetes mellitus due to underlying condition with diabetic nephropathy
E08.21

Registration Number: IRCT20170611034458N3

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients with diabetic nephropathy aged 40 to 75 years
Moderate blood pressure (systolic pressure 140-160 and diastolic pressure 90-100 mm Hg)
Absence of urinary tract infection and any other disease that can cause proteinuria
Glomerular filtration rate more than 60 milliliters per minute.

Exclusion Criteria

Taking antioxidant supplements from three months before entering the study.
Patients who do not want to participate in the study or do not take medication regularly.
Taking steroidal immunosuppressive drugs (corticosteroids).
Suffering from certain cardiovascular diseases, cancer, inflammatory diseases, autoimmune disorders, or hyper- or hypothyroidism.
Taking anticoagulants.
Having high blood pressure (systolic pressure above 140 and diastolic pressure above 90 mm Hg).
pregnancy
Smoking and alcohol use

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum Creatinine. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: Enzymatic assay kit.;Blood Urea Nitrogen. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: Enzymatic assay kit.

Secondary Outcome Measures