Effect of Crocin and Metformin in patients with type 2 diabetes
Phase 3
- Conditions
- Type 2 Diabetes.Type 2 diabetes mellitus
- Registration Number
- IRCT20170611034458N2
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients with type 2 diabetes treated by metformin
Aged 35-75 years old
Exclusion Criteria
Hypertension
Patients with other endocrine, liver, kidney, inflammatory and lung disorders
Taking metformin in combination with other anti-diabetic drugs
Take any other antioxidant supplement
Alcohol-drug abuse
Pregnant women
Patients with type 1 diabetes
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting blood sugar. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: Enzymatic assay kit.;Serum concentrations of insulin. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: ELISA kit.;Hemoglobin A1C levels. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: Enzymatic assay kit.;HOMA-IR. Timepoint: Initially (before the intervention) and at the end (12 weeks after the intervention). Method of measurement: Using available formulas.
- Secondary Outcome Measures
Name Time Method