Common Canister Protocol for Metered Dose Inhaler Administration in Mechanically Ventilated Patients
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 354
- 试验地点
- 2
- 主要终点
- Ventilator-associated pneumonia (VAP)
研究概览
简要总结
Many hospitals employ a common canister inhaler protocol in patients that do not require mechanical ventilator support. Common canister refers to a single inhaler paired with standardized cleaning methods for use on more than one patient. Small reports suggest that this method does not pose an increased infectious risk and is associated with significant cost savings.
Common canister protocols offer a solution to the discordance between inhaler sizes and average inpatient use of the drugs. Metered dose inhaler canisters are contain enough drug for several days to weeks of daily use. However, the average length of stay for most inpatients is only several days. Therefore, most inpatients do not use all of the canister contents, an unused resource that is potentially wasted.
The common canister approach has not been previously described in mechanically ventilated patients (people requiring intensive care unit admission on breathing machines). This study aims to assess the safety of common canister utilization by assessment and comparison of infection rates in the study and control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •mechanically ventilated patients prescribed bronchodilator therapy in a medical intensive care unit
排除标准
- •lung transplant
- •neutropenic
- •contact isolation
结局指标
主要结局
Ventilator-associated pneumonia (VAP)
时间窗: 48 hours after intubation
Pneumonia that developed in association with mechanical ventilation
次要结局
- Inhaler drug cost(During period of mechanical ventilation, which varies depending on patient's severity of illness and reason for intubation; on average may range from 3-5 days.)
研究者
Peggy Watts
MD
Washington University School of Medicine
