Effects of different doses of Naloxone on postoperative hyperparathyroidism
Phase 3
Not yet recruiting
- Conditions
- Hysterectomy.Prolapse of vaginal vault after hysterectomyN99.3
- Registration Number
- IRCT20180723040570N5
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients candidate for hysterectomy
?ASA 1&2
No drug allergy
Exclusion Criteria
Addiction
???Alcohol consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual Analogue Scale. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.;Ramsy score. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.;Pinprick test. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Naloxone's efficacy in mitigating postoperative hyperalgesia after high-dose Remifentanil hysterectomy?
How does Naloxone compare to standard opioid antagonists in managing hyperalgesia in post-hysterectomy patients with vaginal vault prolapse?
Which biomarkers correlate with Naloxone response in patients undergoing hysterectomy with high-dose Remifentanil anesthesia?
What adverse events are associated with Naloxone administration in phase III trials for postoperative hyperalgesia management?
Are there combination therapies involving Naloxone and non-opioid analgesics for post-hysterectomy pain in Iran University of Medical Sciences studies?