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Clinical Trials/NCT06014281
NCT06014281
Active, not recruiting
Not Applicable

An Internet-administered Randomized Control Trial to Examine the Effects of Regular, Brief Meditation Practice on Mental Health and Well Being

Stanford University1 site in 1 country300 target enrollmentNovember 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Stanford University
Enrollment
300
Locations
1
Primary Endpoint
Change in Stroop Test Score
Status
Active, not recruiting
Last Updated
11 months ago

Overview

Brief Summary

The study will examine the effects of online meditation training on stress and anxiety in healthy participants. It will also examine the dose-response relationship between the amount of daily focused attention meditation practice and established mental health outcome measures.

Detailed Description

This is a 16-week study with an 8-week meditation intervention, with a requirement of a minimum of 10 minutes of meditation practice each day. This study will recruit \~200 healthy subjects (18+ years) with no current or previous diagnosis of psychiatric or neurological disorders who are interested in learning about meditation but don't have long-term experience with meditation. Half of the participant pool will be randomly assigned to the meditation intervention, and the other half will get the wait-list control assignment. The control group will later receive its intervention, likely a few weeks after the completion of the active group's intervention. A focused-attention meditation technique (SOS meditation) will be used to train participants. Changes in participants' physiological markers (e.g., HRV, physical activity, respiration rate, sleep quality) will be evaluated using passive activity monitoring devices (e.g., Fitbit). Intervention-related changes in mental health will be assessed using web-based mental health and well-being surveys. Improvements in cognitive functioning will be assessed using web-based psychological tasks.

Registry
clinicaltrials.gov
Start Date
November 1, 2023
End Date
July 30, 2025
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Manish Saggar

Assistant Professor

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years
  • Able to follow basic instructions for prescreening and scheduling
  • Compliant with investigator instructions during the consent process and participation in the study
  • Is not already a regular meditation practitioner

Exclusion Criteria

  • People with a current diagnosis of psychiatric or neurological disorders
  • Be in current psychiatric treatment or medications
  • Hospitalized for psychiatric disorders in the past year or so.
  • Regular and long-term meditation practitioners
  • Non-English speaking
  • Non-USA mailing address to receive the activity tracker device
  • Vision or hearing impairment severe enough to interfere with study participation

Outcomes

Primary Outcomes

Change in Stroop Test Score

Time Frame: Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2)

Using the Stroop test, which measures the average reaction time between incongruent and congruent trials

Resting Heart Rate

Time Frame: Daily (from baseline to week 8 for arm 1 and from week 8 to week 16 for arm 2)

Daily obtained from Activity Tracker wrist band

Change in Generalize Anxiety Disorder Questionnaire Score

Time Frame: Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2)

Anxiety as measured using Generalize Anxiety Disorder Questionnaire

Change in Pittsburgh Sleep Quality Index Questionnaire Score

Time Frame: Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2)

Sleep Quality measured using Pittsburgh sleep quality index (PSQI)

Change in Mind Wandering Questionnaire Score

Time Frame: Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2)

Mind wandering measured using the Mind Wandering Questionnaire

Change in N-back Test Score

Time Frame: Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2)

Using the N-back test is a memory task where participants must remember letters from N trials ago.

Heart Rate Variability

Time Frame: Daily (from baseline to week 8 for arm 1 and from week 8 to week 16 for arm 2)

Daily obtained from Activity Tracker wrist band

Secondary Outcomes

  • Change in Brief Strengths Scale Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change Social Connectedness Scale-Revised Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change in Depression Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change in Quality of Life Scale Measures Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change in Rumination Reflection Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change in Stress Scale Measure Questionnaire Score(Twice (Baseline and week 8 for arm 1 and week 8 and week 16 for arm 2))
  • Change in Sleep Quality Measure(Daily (from baseline to week 8 for arm 1 and from week 8 to week 16 for arm 2))

Study Sites (1)

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