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Clinical Trials/NCT06534957
NCT06534957
Recruiting
Not Applicable

Online Mindfulness-based Stress Reduction Intervention for Patients With Breast Cancer Receiving Chemotherapy

Medicos e Investigadores en la Lucha contra el Cancer de Mama1 site in 1 country200 target enrollmentSeptember 2, 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
Medicos e Investigadores en la Lucha contra el Cancer de Mama
Enrollment
200
Locations
1
Primary Endpoint
Stress
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

The goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based stress reduction (MBSR) intervention reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy.

The main questions it aims to answer are:

  • Does an online MBSR intervention reduce stress levels (measured through the Perceived Stress Scale) among participants?
  • Does an online MBSR intervention reduce anxiety, depression, insomnia, fatigue, nausea, diarrhea, constipation, pain, and peripheral neuropathy (measured through the PRO-CTCAE of the National Cancer Institute) among participants?

Researchers will compare the online MBSR intervention to no intervention to see if online MBSR reduces treatment-related stress.

Participants will:

  • Participate in an online MBSR intervention or no intervention for 6 weeks
  • Answer the study surveys at baseline, 7 weeks, and 11 weeks of follow-up
Registry
clinicaltrials.gov
Start Date
September 2, 2025
End Date
April 1, 2026
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Medicos e Investigadores en la Lucha contra el Cancer de Mama
Responsible Party
Principal Investigator
Principal Investigator

Fernanda Mesa-Chavez

Principal Investigator

Medicos e Investigadores en la Lucha contra el Cancer de Mama

Eligibility Criteria

Inclusion Criteria

  • Female sex
  • Age ≥18 years
  • Diagnosis of non-metastatic breast cancer
  • Plan to start neoadjuvant or adjuvant chemotherapy in \<4 weeks
  • Internet access at home or in their mobile phone
  • Availability to participate in the online MBSR intervention for 6 weeks
  • Availability to answer the study surveys
  • Provision of signed informed consent

Exclusion Criteria

  • Disease recurrence
  • Current meditation or mindfulness practice
  • Inability to read or write

Outcomes

Primary Outcomes

Stress

Time Frame: 11 weeks

Measured through the Perceived Stress Scale (PSS). The PSS is a self-report instrument that assesses the level of perceived stress over the past month. It consists of 10 items that are rated using a 5-point Likert scale (0: Never; 1: Almost never; 2: Sometimes; 3: Fairly often; 4: Very often). The total score is obtained by adding the scores of the 10 items, obtaining a total value between 0-40, where higher scores indicate a higher level of perceived stress. A moderate stress level is considered between 20-25 points, and a high stress level is considered when obtaining \>25 points.

Study Sites (1)

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