Blood Components Changes by Using of Ringer's Lactated as Detergent In Autologous Blood Cell Transfusion
- Conditions
- Placenta Accreta Spectrum
- Interventions
- Other: Ringer's Lactated
- Registration Number
- NCT04927988
- Lead Sponsor
- Maternal and Child Health Hospital of Foshan
- Brief Summary
Placenta accreta spectrum (PAS) disorders are associated with increased maternal morbidity and mortality related to life-threatening hemorrhage, and greater potential need for blood transfusion. Clinical evidences have confirmed that the use of autologous blood cell transfusion is safe and effective for patients with obstetric haemorrhage. Normal saline is the solution recommended for red cell washing, administration and salvage. However, there is growing concern that normal saline is more toxic than balanced, buffered crystalloids such as Lactated Ringer's and Plasma-Lyte. The purpose of this study is to evaluate the blood components using of Ringer's Lactated by a prospective, single-center, open, and single-arm clinical trial.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- Female
- Target Recruitment
- Not specified
- Between 18 and 45 years old
- Without health problem nor disease requiring regular medical treatment
- subject with contraindication for drawing blood
- Subject with physical or mental disability or restriction of liberty that would prevent autotransfusion
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Arm 1. Ringer's Lactated Using of Ringer's Lactated
- Primary Outcome Measures
Name Time Method Change in hematological parameters Baseline (Day 1), until 2 days after autotransfusion Mean corpuscular volume (fL)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Maternal and Child Health Hospital of Foshan
🇨🇳Foshan, Guangdong, China