Screening Latent Tuberculosis Infection and Observing Preventive Therapy in Kidney Transplantation

Not Applicable

• Conditions: Kidney Transplantation

• Registration Number: NCT02782416
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB

Detailed Description

Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB

Study Timeline

• Study Start: 2014-01
• Study First Submitted: 2016-05-11
• Study First Submitted QC: 2016-05-22
• Study First Posted: 2016-05-25
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-13
• Last Update Posted: 2016-12-15
• Primary Completion: 2017-12
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

1. Age between 20-65 and match one of below
2. Waiting renal transplant or status post renal transplant
3. Receiving long term dialysis

Exclusion Criteria

1. Not agree to be enrolled
2. Suspected active TB
3. HIV patients
4. Viral hepatitis
5. Using immunosuppressants within 3 months before enrollment
6. Receiving lymphokine therapy
7. Hemoglobin < 8 g/dL
8. Serum bilirubin > 2.5 mg/dL
9. AST or ALT > 2 times of upper normal limit
10. Lactation or pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
percentage of active TB	4 years

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan