Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World Data: An Initiative by the Korean Adrenal Disorder Study (KADS) Group
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 8,200
- 试验地点
- 1
- 主要终点
- Incidence rate of cardiovascular event
研究概览
简要总结
This research aims to establish clinical evidence for optimal treatment guidelines for adrenal diseases using real-world data. The approach involves building prospective and retrospective patient registries, which will be utilized to develop and conduct research on disease-specific protocols for adrenal disorders. The study targets patients with primary aldosteronism, pheochromocytoma, adrenal cancer, adrenal incidentalomas, and mild autonomous cortisol secretion. Registries for patients with adrenal diseases will be obtained from Seoul National University Hospital and Asan Medical Center, along with securing a common data model. The ultimate goal is to conduct research to generate clinical evidence for adrenal diseases using these resources.
详细描述
The ultimate goal is to develop clinical evidence for unmet needs in adrenal gland diseases using real-world data, thereby contributing to the optimization of treatment guidelines. This involves:
- Generating real-world healthcare data through prospective and retrospective registries specific to each adrenal disease.
- Acquiring a common data model for adrenal diseases, applicable across both domestic and international multicenter settings.
- Creating real-world data linked with hospital medical records and public data for each adrenal disease, utilizing anonymized information merging services.
- Developing and conducting research based on prospective and retrospective registries, a common data model, and the utilization of public-medical data for different adrenal diseases.
Study Design:
Prospective and retrospective patient registries.
Study Population:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with adrenal diseases such as adrenal cortical carcinoma, Cushing's syndrome, primary aldosteronism, pheochromocytoma, adrenal incidentaloma
- •patients who are 19 years or older
排除标准
- •patients younger than 19 years old
结局指标
主要结局
Incidence rate of cardiovascular event
时间窗: up to 20years
Cardiovascular event
次要结局
- Mortality rate(up to 20years)
研究者
Jung Hee Kim
Associate professor
Seoul National University Hospital