Effectiveness of pentoxifylline in contrast induced nephropathy

Phase 2

• Conditions: Contrast Nephropathy.; Renal failure; N17, N18,

• Registration Number: IRCT2015102624713N1
• Lead Sponsor: Vice chancellor for research,Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Inclusion criteria of ckd patients with angiography and cardiac catheterization indication include:Age greater than 18 and less than 75 years,Patient satisfaction for the study
Exclusion criteria include : problems in patients follow up, treatment with theophylline, furosemide, mannitol or dopamine in last one month,use of Nonsteroidal anti-inflammatory drugs, aminoglycosides, N-acetylcysteine drugs,Renal failure patients with serum creatinine equal to or less than 1.5 mg per deciliter, Patients with an allergy to contrast material, Patients with Multiple myeloma, Pulmonary edema, Uncontrolled hypertension, patient required emergency angiography,
diagnostic use of radiocontrast material for patient in the last 2 months of other diagnostic reasons, congestive heart failure,pregnancy, lactation
Sensitivity to the NAC or pentoxifylline

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum Creatine. Timepoint: at admission, 24 h after intervention. Method of measurement: blood test based on miligram on decilitre.

Secondary Outcome Measures

Name	Time	Method
Contrast Nephropathy. Timepoint: 24 houres. Method of measurement: blood test based on miligram on decilitre.