Transpulmonary Pressures in Mechanical Ventilated Patients With Morbid Obesity

Completed

• Conditions: Respiratory Insufficiency; Mechanical Ventilation Complication

• Registration Number: NCT02309190
• Lead Sponsor: The University of Texas Health Science Center, Houston

Brief Summary

The study consists in determine the transpulmonary pressure in morbidly obesity patients that require mechanical ventilation.

* both gender

* only adults

* Medical intensive care patients.

Detailed Description

We are studying adult patients with morbid obesity with respiratory failure requiring mechanical ventilation.

We are measuring transesophageal presssures to estimate ideal PEEP and evaluate hemodynamic parameters.

Study Timeline

• Study First Submitted: 2014-09-16
• Study First Submitted QC: 2014-12-02
• Study First Posted: 2014-12-05
• Study Start: 2018-01-01
• Status Verified: 2024-12
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-01
• Last Update Submitted: 2024-12-06
• Last Update Posted: 2024-12-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• both gender
• morbid obesity
• hemodynamically stable

Exclusion Criteria

• pregnant patients
• cirrhotic patients with esophageal varicose

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transpulmonary pressure	one year	We will record the changes in transpulmonary pressure after adjusting PEEP (measure in cmH2O).

Secondary Outcome Measures

Name	Time	Method
hemodynamics	one year	we will review hemodynamic changes while adjusting PEEP (BP, HR).

Trial Locations

Locations (1)

The University of Texas - HSC at Houston; 🇺🇸 Houston, Texas, United States