Wet-wrap treatment in children with atopic dermatitis using the wet-wrap method with diluted corticosteroids versus emollients
- Conditions
- atopic dermatitisatopic eczemawet-wrap therapyatopisch eczeemconstitutioneel eczeememollients
- Registration Number
- NL-OMON21806
- Lead Sponsor
- Charlotte van Sassen, KinderHaven, Havenziekenhuis Rotterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1. Age 6 months - 6 years at inclusion
2. Diagnosis of atopic dermatitis with an objective SCORAD > 40
Exclusion Criteria
1. Known pre-existing, serious underlying disease
2. (Secondary) infected eczema:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main endpoint concerns the comparison of the decrease of the objective SCORAD between the two groups for the various time points (=comparison of efficacy of the two therapies).
- Secondary Outcome Measures
Name Time Method One secondary endpoint is the change of serum markers levels at various time points in the two groups and the correlation of the serum markers levels to the objective SCORAD (=development of an effective and objective value for monitoring the severity of AD)<br>Another secondary endpoint is change in quality of life-score at the beginning and the end of the study in the two groups and the correlation of the quality of life score to the objective SCORAD and the serum markers. <br>