This study evaluates the relationship between sleep, internal body clock which determines normal functioning of the body and physical activity levels assessed in patients with head and neck cancer recieving chemoradiotherapy treatment.
Not Applicable
Completed
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2020/01/022877
- Lead Sponsor
- Manipal Institute of Higher Education
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 27
Inclusion Criteria
A) Patients diagnosed with head and neck cancer stage 3, 4A and 4B
B) Patients undergoing chemoradiotherapy
C) Pre-operative or post-operative status
D) Eastern Cooperative Oncology Group (ECOG) score <2
Exclusion Criteria
A) Patients with reduced alertness
B) Patients with non-ambulatory status
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sleep quality-sleep onset latency, total sleep time and sleep efficiency <br/ ><br>circadian rhythm- 24-hour correlation coefficient and in bed and out of bed dichotomy index <br/ ><br>physical activity- METs and step countTimepoint: sleep quality-sleep onset latency, total sleep time and sleep efficiency <br/ ><br>circadian rhythm- 24-hour correlation coefficient and in bed and out of bed dichotomy index <br/ ><br>physical activity- METs and step count
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways link circadian rhythm disruption to treatment outcomes in head and neck cancer patients undergoing chemoradiotherapy?
How does objective sleep monitoring compare to standard-of-care assessments in predicting toxicity in CTRI/2020/01/022877 head and neck cancer patients?
Which circadian rhythm biomarkers correlate with physical activity levels in C00-C14 malignant neoplasm patients during chemoradiotherapy?
What adverse events are associated with circadian misalignment in head and neck cancer patients receiving concurrent chemoradiotherapy?
How do circadian rhythm modulators like melatonin or chronotherapy agents influence physical activity and survival in head and neck squamous cell carcinoma patients?