NCT02571699Unknown不适用
Minimum Effective Volume of Lidocaine-Bupivacaine for Ultrasound-Guided Subgluteal Sciatic Nerve Block
McGill University Health Centre/Research Institute of the McGill University Health Centre2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2016年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- success rate
研究概览
简要总结
The aim of this study is to determine the minimum effective volume of LA in 90 % of patients (MEV90) required for US-guided subgluteal sciatic nerve block.
详细描述
The aim of this study is to determine the minimum effective volume of LA in 90 % of patients (MEV90) required for US-guided subgluteal sciatic nerve block.
Success rate is defined as a minimal composite score of 6 points (out of 8 points) at 30 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age between 18 and 75 years
- •American Society of Anesthesiologists classification 1-3
- •body mass index between 20 and 35
排除标准
- •adults who are unable to give their own consent
- •pre-existing neuropathy (assessed by history and physical examination)
- •coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. platelets≤ 100, International Normalized Ratio≥ 1.4 or partial prothrombin time ≥ 50)
- •renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. creatinine ≥ 100)
- •hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. transaminases ≥ 100)
- •allergy to LA
- •pregnancy
- •prior surgery in the subgluteal region
- •chronic pain syndromes requiring opioid intake at home
结局指标
主要结局
success rate
时间窗: 0-30 minutes
minimal composite score of 6 out of 8 points
次要结局
未报告次要终点
研究者
De Tran
Associate Professor
McGill University Health Centre/Research Institute of the McGill University Health Centre
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Minimum Effective Volume of Lidocaine Costoclavicular Brachial Plexus BlockUpper Extremity SurgeryNCT02932670McGill University Health Centre/Research Institute of the McGill University Health Centre60
终止
不适用
MEV for Retroclavicular Approach to Infraclavicular BlockBupivacaineNCT03555786Antalya Training and Research Hospital45
已完成
不适用
Retroclavicular Approach to Infraclavicular BlockBupivacaineNCT03472911Antalya Training and Research Hospital25
已完成
不适用
Minimum Effective Dose of 0.5% Bupivacaine for Ultrasound-guided Spinal Anesthesia Using Taylor's ApproachLower Limb SurgeryNCT03899038Huazhong University of Science and Technology56
已完成
不适用
Determining the Minimum Effective Volume of Local Anesthetic for Ultrasound-guided Axillary Brachial Plexus BlockAxillary Brachial Plexus BlockNCT01421914Federal University of São Paulo19