An observational study of the gas flow delivered by bubble continuous positive airway pressure (CPAP) to preterm infants in neonatal intensive care

Not Applicable

Completed

• Conditions: Respiratory Distress Syndrome; Respiratory - Other respiratory disorders / diseases; Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12619000197134
• Lead Sponsor: Department of Newborn Research, The Royal Women's Hospital Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-12
• Study Completion: 2019-09-11
• Last Update Posted: 22 October 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

Infants born less than 37 weeks gestation.
- Currently receiving bubble CPAP therapy for any reason in the neonatal intensive care unit (NICU).
- Agreement from the treating clinician to include the infant in the study.
- Informed consent for participation in the study provided by the parent or guardian.

Exclusion Criteria

- Informed consent refused or withdrawn by a parent or guardian.
- Unstable clinical condition, including but not limited to respiratory distress and varying oxygen saturation.
- Deemed unsuitable by the treating clinician for participation in the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gas flow in litres per minute delivered by bubble CPAP at a range of set pressures to the nose of preterm infants. <br>CPAP pressure will be monitored via a pressure monitor connected to the inspiratory limb of the system. Gas flow to the infant will be read from the flow meter in L/min once bubbling has ceased in the bubble chamber.[At time of observation.]

Secondary Outcome Measures

Name	Time	Method
Gas flow changes in litres per minute with mouth opened or closed.<br>Gas flow to the infant will be read from the flow meter in L/min once bubbling has ceased in the bubble chamber. Mouth opening will be assessed as either open or closed by observation.[At time of observation.]