Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI) Inhibitors and Undergoing Intervention of Heart Surgery on Pump

Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria1 site in 1 country152 target enrollmentJune 4, 2020

ConditionsDelirium

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Delirium
Sponsor: Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Enrollment: 152
Locations: 1
Primary Endpoint: Presence/absence of postoperative delirium
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The study aims to observe the presence of postoperative delirium in patients undergoing elective cardiac surgery, without changing the pharmacological prescriptions of the enrolled patients and the procedures carried out by normal clinical practice.

Registry

clinicaltrials.gov

Start Date

June 4, 2020

End Date

September 15, 2021

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•patients over 18 years old
•patients undergoing elective cardiac surgery
•patients diagnosed with depressive syndrome requiring treatment with Inhibitors of serotoninergic reuptake excluding neurodegenerative diseases
•patients on antidepressant therapy for more than 3 months at the time of enrollment

Exclusion Criteria

•absence of written informed consent to the study
•patients undergoing non-elective and emergency cardiac surgery
•patients undergoing off pump surgery
•patients with depression not on therapy
•patients with existing malignancies
•patients with acute infections in progress
•patients with previous stroke, cerebral haemorrhage with relics
•patients with acquired and congenital metabolic pathologies with CNS alterations
•Patients with acute and / or chronic renal failure according to RIFLE score (exclude only F-L-E)
•Patients with acute and / or chronic hepatic insufficiency according to Child - Pugh score \<6 (but without encephalopathy);