The relation between cognitive performance and decision making: modulation with modafinil
- Conditions
- geen aandoeningnot applicable
- Registration Number
- NL-OMON49250
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 142
• In the opinion of the investigator, the participant is capable of
understanding and complying with protocol requirements.
• The participant is male or female.
• The participant has a body mass index of 18.5-30 kg/m2, inclusive, as stated
in the medical screening form.
• The participant is aged 18 to 40 years, inclusive, at the time of informed
consent.
• The volunteer is healthy, i.e., the absence of all exclusion criteria and had
normal or corrected to normal static binocular acuity with or without
correction.
• The participant signs and dates a written informed consent form before the
start of the experiment.
• The subject has an uncontrolled, clinically significant neurologic,
cardiovascular, pulmonary, hepatic, renal, metabolic, gastrointestinal, or
endocrine disease or other abnormality which may impact the ability of the
subject to participate or potentially confound the study results.
• The volunteer has uncontrolled existing major psychiatric symptoms.
• The participant has known hypersensitivity to any component of the
formulation or Modafinil or related compounds.
• The subject has a history of drug abuse (defined as any illicit drug use) or
a history of alcohol abuse within 1 year prior to the first visit or is
unwilling to agree to abstain from alcohol from 24 hours prior to each test day
and/or drugs throughout the study.
• The participant has any sensory or motor deficits which could reasonably be
expected to affect test performance.
• Other exclusion criteria are smoking, excessive drinking (>20 glasses of
alcohol-containing beverages a week), use of medication.
• For females, exclusion criteria are taking the birth control pill and being
pregnant.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are behavioral data from economic decision-making<br /><br>paradigms. In particular, elicited parameters describing preferences over risk,<br /><br>time, and losses. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Social preferences, trust, and reciprocity are secondary parameters, as well as<br /><br>cognitive performance on our control tasks. </p><br>