Correlation Between Serum Progesterone Level And Menstrual Symptoms In Young Females With Primary Dysmenorrhea
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Serum progesterone level
研究概览
简要总结
This study will be conducted to determine the correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females with primary dysmenorrhea.
详细描述
One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynaecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young females with primaryf dysmenorrhea.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 17 Years 至 25 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •One hundreds adult females were suffered from primary dysmenorrhea.
- •Their age was ranged from 17 to 24 years.
- •Their body mass index was ranged from 20 to 25 kg/m2.
排除标准
- •Any participant will be excluded from the study if they have:
- •Irregulars or infrequent menstrual cycles.
- •Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis.
- •Pelvic pathology.
结局指标
主要结局
Serum progesterone level
时间窗: 1 month
Blood samples will be taken by physician for each girl, and will send to laboratory center to measure the progesterone level in the blood. The normal serum progesterone level at 21st day is 4-20 ng
Pain intensity
时间窗: 1 month
It will be measured by Visual analogue scale. It is 10 cm line with values ranging from 0 to 10. 0 indicates no pain nd 10 indicates the worst pain.
Physical and psychological menstrual symptoms
时间窗: 1 month
It will be measured by menstrual symptoms questionnaire. It is 25 items split into two categories which used to assess the physical and psychological symptoms associated with dysmenorrhea. The score on each item ranged from 1 (never) to 5 (always) with a higher composite score indicating more symptoms
Correlation between serum progesterone level and pain
时间窗: 1 month
The correlation between serum progesterone level and pain intensity measured by the VAS will be conducted
Correlation between serum progesterone level and menstrual symptoms
时间窗: 1 month
The correlation between serum progesterone level and menstrual symptoms measured by the menstrual symptom questionnaire will be conducted
次要结局
未报告次要终点
研究者
Mennaallah Yousef Mohamed Nasreldien
Lecturer of physical therapy for women's health
Cairo University