Correlation Between Serum Progesterone Level And Primary Dysmenorrhea
- Conditions
- Primary Dysmenorrhea
- Registration Number
- NCT06359457
- Lead Sponsor
- Cairo University
- Brief Summary
This study will be conducted to determine Correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females
- Detailed Description
One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from outpatient clinic of Gynaecological outpatient clinic, faculty of physical therapy, Cairo university, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young female complain of dysmenorrhea and non-dysmenorrhea.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Female
- Target Recruitment
- 100
- One hundreds adult females were suffered from primary dysmenorrhea.
- Their age was ranged from 17 to 24 years.
- Their body mass index was ranged from 20 to 25 kg/m2.
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Any participant will be excluded from the study if they have:
- Irregulars or infrequent menstrual cycles.
- Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis.
- Pelvic pathology.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum progesterone level Up to 3 months Blood samples will be taken by physician for each girl, and will send to laboratory center to measure the progesterone level in the blood. The normal serum progesterone level at 21st day is 4-20ng
Pain intensity Up to 3 months It will be measured by Visual analogue scale. It is a graphic rating scale with numerical values placed equidistantly along the line. The descriptors and numbers help the subject to place her estimate on line in which 0 mean no pain,1 equal mild pain, 2 equal moderate pain, 3 mean sever pain and 4 mean unbearable pain.
Physical and psychological symptoms Up to 3 months It will be measured by menstrual symptoms questionnaire. It was 13 item of 22 item of c-form MSQ (CMSQ) which used to assess the physical and psychological symptoms associated with dysmenorrhea.The score on each item ranged from 1 (never) to 5 (always) with a higher composite score indicating more symptoms
- Secondary Outcome Measures
Name Time Method