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Clinical Trials/NCT03367923
NCT03367923
Completed
Phase 2

Step Into Wellness: A Program of Health and Recovery for Endometrial Cancer Survivors

Stanford University2 sites in 1 country47 target enrollmentDecember 1, 2017

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Cancer Survivor
Sponsor
Stanford University
Enrollment
47
Locations
2
Primary Endpoint
Increase in activity level measured using Fitbit tracker
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This randomized phase II trial studies how well a health and recovery program works in increasing physical activity level in stage IA-IIIA endometrial cancer survivors. Health and recovery program which includes exercise counseling, Fitbit tracker, and phone or email/text communication may increase the level of physical activity in endometrial cancer survivors and promote and maintain behavior change at a lower cost.

Detailed Description

PRIMARY OBJECTIVES:I. Determine the increase in activity level per participant where the baseline average number of steps is recorded during week 0-2 will be compared to average step count recorded during week 20-28.SECONDARY OBJECTIVES:I. Determining the rate of patients who have achieved a 50% increase in activity level in each communication group (telephone versus \[vs.\] electronic).II. Demonstrate that the rate of patients who have achieved an increased activity level of 50% as compared to the patient's baseline in the electronic/email group is not inferior to the rate in the telephone group.III. Evaluate changes in body mass index (BMI), waist circumference, blood pressure and pulse for the whole group, by communication group (electronic vs. telephone), and by activity level.IV. Evaluate the changes in quality of life, as assessed by Functional Assessment of Cancer Therapy-General (FACT-G), during the course of the study for the whole group, between the two groups (electronic vs. telephone), and based on activity level.V. Evaluate maintenance of activity level at 9 month (m) (week 32-40) (comparison activity level 9 m vs. 6 m) for the whole group, by group (electronic vs. telephone), and by activity level.OUTLINE: Patients are randomized to 1 of 2 arms.ARM I: Participants undergo an exercise counseling session at baseline and wear Fitbit tracker daily for 9 months. Participants receive a short phone call at 2, 4, 6, and 8 weeks, and at 4 and 5 months to discuss the average number of daily steps over the past 2 weeks and to encourage a goal of a 10% increase over the next 2-4 week time period.ARM II: Participants undergo an exercise counseling session at baseline and wear Fitbit tracker daily for 9 months. Participants receive an electronic communication (email/text) of their choice at 2, 4, 6, and 8 weeks, and at 4 and 5 months stating the average number of daily steps over the past 2 weeks and encouraging a goal of a 10% increase over the next 2-4 week time period.

Registry
clinicaltrials.gov
Start Date
December 1, 2017
End Date
March 25, 2020
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Stage IA-IIIA endometrial cancer patients with pathology reviewed at Stanford
  • Patients must have undergone surgery as a part of their treatment for their endometrial cancer
  • At least 3 months post treatment
  • BMI \> 25
  • Life expectancy of at least one year
  • Able to perform physical activity of walking
  • Possession of a computer and/or smart phone and/or smart tablet
  • Must be English or Spanish speaking

Exclusion Criteria

  • Other active cancer
  • Receiving chemotherapy or other active treatment
  • BMI \< 60
  • Diagnosis of uterine serous carcinoma or uterine sarcoma

Outcomes

Primary Outcomes

Increase in activity level measured using Fitbit tracker

Time Frame: Up to week 20-28

The increase in activity level will be determined where the baseline average number of steps recorded per patient during week 0 - 2 will be compared to the average step count recorded during week 20 - 28. The baseline measurement will be defined as the average step count reported by the patient during 0-2 weeks. At each subsequent time point the average step count per patient will be the average of the step counts recorded during the 2-4 weeks prior to the follow up visit. The average step count measured at 20-28 weeks will be compared to the baseline in a paired t test. The paired t test will

Secondary Outcomes

  • Body mass index (BMI)(Up to 9 months)
  • Pulse(Up to 9 months)
  • Quality of life assessment using Functional Assessment of Cancer Therapy-General (FACT-G)(Up to 9 months)
  • Blood pressure(Up to 9 months)
  • Rate of increased activity level measured using Fitbit tracker(Up to 9 months)
  • Waist circumference(Up to 9 months)

Study Sites (2)

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