Kinetics of solute removal with on-line hemodiafiltration: influence of duration and frequency of treatment

Completed

• Conditions: End stage renal disease; Nutritional, Metabolic, Endocrine; Renal disease

• Registration Number: ISRCTN45403612
• Lead Sponsor: Gambro Dialysatoren GmbH (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-02-02
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Stable patients with renal end stage disease being on hemodialysis for at least six months
2. Residual urine volume less than 200 ml per day
3. Ages betweeen 18 and 75 years
4. Body dry weight between 60 and 80 kg
5. Written consent
6. Well functioning vascular access

Exclusion Criteria

1. Known human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV) infection
2. Miscellaneous acute or chronic infections
3. Known coagulation disturbances
4. Known incompliance with respect to fluid restriction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood concentrations of small and large molecular weight uremic solutes

Secondary Outcome Measures

Name	Time	Method
Modelling of solute kinetics