The Impact of Preemptive Epidural Analgesia on Acute Postoperative Pain in Pediatric Orthopedic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- FLACC scale score (Face, Legs, Activity, Cry, Consolability)
研究概览
简要总结
Management of postoperative pain is critical in the pediatric patients, however, safe and effective analgesia for pediatric surgical patients remains a challenge. Preemptive analgesia is based on preventing a prolonged change in central nervous system function by blocking afferent input before the surgical stimulation may evoke central sensitization and aggravate amplification and prolongation of postoperative pain. However, the clinical efficacy of preemptive analgesia is still controversial. In this study, the investigators aim to assess the impact of preemptive epidural analgesia on postoperative pain in pediatric patients for corrective osteotomy of the lower extremities expecting severe postoperative pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 3 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pediatric patients (3-12 years of age) scheduled for corrective osteotomy of the lower extremities
- •ASA class I and II
排除标准
- •Coagulopathy
- •Neurological disease
- •Allergy to local anesthetics or contraindication to use of ropivacaine
- •Infection at the site of epidural catheter insertion
研究组 & 干预措施
preemptive group
Group who will be received ropivacaine bolus and continous infusion 5 minutes before skin incision.
干预措施: 0.2 ml/kg of 0.2% ropivacaine (Procedure)
saline group
Group who will be received saline bolus and continous infusion 5 minutes before skin incision
干预措施: 0.2mg/kg of Normal Saline (Procedure)
结局指标
主要结局
FLACC scale score (Face, Legs, Activity, Cry, Consolability)
时间窗: 0-6 hours after the operation
次要结局
未报告次要终点