Effect of peri-operative transfusion of blood products on pulmonary leakage measured with the pulmonary leakage index in a cohort of cardiac surgery patients.

• Conditions: Bloedtransfusie reacties; Transfusion reaction

• Registration Number: NL-OMON30813
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Cardiac surgery patients with post operative ICU admittance
Informed consent
>18 years
Recieving a minimum of 2 Fresh Frozen Plasma, 2 Packed Cells, 1 unit of platelets

Exclusion Criteria

Immunosuppressive drugs

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>PLI</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>HLA/HNA typing of transfusion<br /><br>Concentration of LysoPCs in transfusion material<br /><br>Concentration of inflamation markers in the broncho alveolair lavage</p><br>