Simultaneous Injection of Propofol and Rocuronium in Inducing General Anesthesia

Not Applicable

Completed

• Conditions: Anesthesia; Functional
• Interventions: Drug: administration of propofol and rocuronium

• Registration Number: NCT03270696
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study is conducted to evaluate the efficacy of simultaneous injection of propofol and rocuronium in inducing general anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-23
• Study First Submitted: 2017-08-23
• Study First Submitted QC: 2017-08-30
• Status Verified: 2017-09
• Study First Posted: 2017-09-01
• Primary Completion: 2018-01-30
• Study Completion: 2018-01-30
• Last Update Submitted: 2018-04-11
• Last Update Posted: 2018-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

• patients undergoing elective surgery requiring endotracheal intubation
• ASA I, II, and III
• above 20 years

Exclusion Criteria

• refuse to enroll
• patients with risk of aspirating gastric contents
• patients in whom NMBs are contraindicated
• patients with predictors of difficult mask ventilation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ordinal administration of propofol and rocuronium	administration of propofol and rocuronium	In this group, the investigator will administrate propofol (2ml/kg) first, and follow injection of rocuronium (0.6mg/kg) after patient loss consciousness and confirming facemask ventilation. The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.
simultaneous administration of propofol and rocuronium	administration of propofol and rocuronium	In this group, the investigator will administrate propofol (2ml/kg) and rocuronium (0.6mg/kg) simultaneously, and start facemask ventilation after patient loss consciousness to induce general anesthesia. The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.

Primary Outcome Measures

Name	Time	Method
mean tidal volume	from starting facemask ventilation for 1 minute	mean tidal volume of facemask ventilation in 1 minute

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of