Cerebral blood flow measurements with fMRI.
Recruiting
- Conditions
- Bestuderen van de bloeddoorstroming van de hersenen in reactie op een hoog calorische stimulus.To study cerebral blood flow with 1Tesla MRI before and after ingestion of a liquid meal.
- Registration Number
- NL-OMON23542
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1. 15 lean male subjects/ 15 lean female subjects;
2. BMI 20- 25 kg/m²;
Exclusion Criteria
1. Claustrophobia;
2. Metal objects in the body (e.g. pacemaker);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage and/or absolute changes in local cerebral blood flow after a liquid meal.
- Secondary Outcome Measures
Name Time Method 1. Difference in cerebral blood flow between males and females;<br /><br>2. Influence of ingestion of a liquid meal.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie cerebral blood flow changes after high-caloric liquid meal ingestion in healthy individuals?
How does 1Tesla fMRI compare to standard 3Tesla fMRI in measuring cerebral blood flow responses to nutritional stimuli?
Are there specific biomarkers that correlate with cerebral blood flow modulation in response to caloric intake?
What adverse events are associated with cerebral blood flow measurement using low-field fMRI in clinical studies?
How do postprandial cerebral blood flow patterns in lean individuals relate to metabolic disorders like obesity or diabetes?