Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty

Not Applicable

Completed

• Conditions: Osteoarthritis, Hip
• Interventions: Procedure: local infiltration anesthesia using saline; Procedure: local infiltration anesthesia using Ropivacaine and Epinephrine; Procedure: Multimodal analgesic regimen

• Registration Number: NCT02359136
• Lead Sponsor: St. Olavs Hospital

Brief Summary

Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA). However, the evidence for LIA in THA remains to be clarified.

Purpose: To evaluate whether a single shot LIA in addition to a multimodal analgesic regimen reduces acute postoperative pain and opioid requirements after THA.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-03
• Primary Completion: 2014-03
• Study Completion: 2015-01
• Study First Submitted: 2015-02-04
• Study First Submitted QC: 2015-02-06
• Study First Posted: 2015-02-09
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-30
• Last Update Posted: 2017-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• all patients receiving total hip arthroplasty in the study period

Exclusion Criteria

• contraindications to receive spinal anesthetic, Dexamethasone or Acetaminophen.
• Patients who received general anaesthetic
• patients who will get a different operation than standard direct lateral surgery
• Patients with osteosynthesis to be removed in the same operation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
LIA placebo	local infiltration anesthesia using saline	local infiltration anesthesia using saline i addition to multimodal analgesic regimen
LIA Ropivacaine	Multimodal analgesic regimen	local infiltration anesthesia using Ropivacaine and Epinephrine i addition to multimodal analgesic regimen
LIA Ropivacaine	local infiltration anesthesia using Ropivacaine and Epinephrine	local infiltration anesthesia using Ropivacaine and Epinephrine i addition to multimodal analgesic regimen
LIA placebo	Multimodal analgesic regimen	local infiltration anesthesia using saline i addition to multimodal analgesic regimen

Primary Outcome Measures

Name	Time	Method
postoperative pain assessed by numeric rating scale	1 day (first postoperative day)	assessed by numeric rating scale

Trial Locations

Locations (1)

St.Olavs Hospital, Department of Orthopedics; 🇳🇴 Trondheim, Norway