Effects of Non-Invasive Ventilation During Sleep in Patients with Chronic Obstructive Pulmonary Disease (COPD)

Not Applicable

• Conditions: Sleep; F02.830.855

• Registration Number: RBR-2s29md
• Lead Sponsor: niversidade Federal do Ceará

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-25
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Adult patients; over 40 years old; diagnosed with COPD by spirometric criteria, classified as moderate or severe; with stable disease characterized by the absence of exacerbation for more than 2 months; with absence of other pulmonary, cardiovascular, renal and neurological morbidities; and who signed the informed consent form

Exclusion Criteria

Patients who did not complete the study protocol; and who did not sign the free and informed consent form

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome: Evaluation of the acute effects of noninvasive ventilation (NIV) on sleep latency and phases, and on the occurrence of respiratory events during sleep, in patients with COPD. This analysis was performed by comparing the quantitative data between the two polysomnography exams (without NIV and with NIV).

Secondary Outcome Measures

Name	Time	Method
Secondary outcome: Evaluation of the acute effects of noninvasive ventilation (NIV) on arterial hypoxemia and heart rate (HR) during sleep in patients with COPD. This analysis was performed by comparing the quantitative data between the two polysomnography exams (without NIV and with NIV).