Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 2,530
- Locations
- 26
- Primary Endpoint
- incidence of acute respiratory distress syndrome (ARDS)
Study Overview
Brief Summary
The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue. No large nationwide, multicenters study of ARDS has been conducted in China. The purposes of this study are to analyse: 1)the incidence and outcomes of ARDS in ICU; 2) factors associated the mortality ; and 3) risk factors for development of ARDS .
Detailed Description
All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 ) will be screened at ICU admission and daily for the occurrence of ARDS ( AECC criteria) for a maximum of 28 days after ICU admission.
Data collection:
- For all patients, Demographic characteristics, admission category, the patient source intervention during ICU , APACHEII , SOFA score and discharge information will be collected
- For patients with ARDS, data about ABG , parameters of MV, hemodynamic on day0 to day7 and last day of MV will be collected.
- For patients without ARDS at ICU admission, data about risk factor for ARDS ,such as LIPS score, parameters of MV , and fluid balance on ICU day0 to day7 will be collected.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •all patients age >18 yrs admitted to 24 participating ICUs
Exclusion Criteria
- •No patients should be excluded (regardless of age, underlying disease, life expectancy, etc).
Outcomes
Primary Outcomes
incidence of acute respiratory distress syndrome (ARDS)
Time Frame: from ICU admission to 28-day of ICU stay
incidence of ARDS = the number of patients developing ARDS during ICU / the total number of patients admitted to ICU
Secondary Outcomes
- ICU mortality of patients with ARDS(followed up to 3 months after inclusion or to ICU discharge, whichever occurred first)
- hospital mortality of patients with ARDS(followed up to 3 months after inclusion or to hospital discharge, whichever occurred first)