A Realworld Study of Acute Respiratory Distress Syndrome in China
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
ARDS is a critical respiratory disease caused by endogenous and exogenous factors. The mortality of ARDS varies from 30 to 70%. In 2012, a new international diagnostic criterion has been put forward. Yet, its feasibility, reliability and validity need to be tested. Meanwhile, the correlation of different severity and prognosis remains unclear. As so far, the epidemiological information about ARDS in China is lacking.
Investigators plan to conduct a multi-center observational study（real-life study） to investigate the risk factors, morbidity, management and prognosis of ARDS in China, in order to facilitate standardization of diagnosis and management of ARDS and provide basic data and idea for further clinical intervention studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥18 years of age; hospitalized patients with main diagnosis as ARDS.
排除标准
- •<18 years of age
- •Patients or their families refused to participate in the study
- •Patients diagnosed as COPD, pulmonary fibrosis or bronchiectasis
结局指标
主要结局
Mortality
时间窗: 28days
the 28days mortality after the diagnosis of ARDS
次要结局
- Incidence of ARDS(2 years)
- Number of patients with high risk factors(1 week)
- Length of ICU stay(90 days)
- Ventilation free days(28 days)
- Number of patients using adjuvant drugs(28 days)
- Number of patients with impaired lung function(90 days, 1 year)
- Severity of patients(2 years)
- Number of patients with conventional respiratory support techniques(28 days)
- Adverse events related to treatment(90 days)
- Number of patients with unconventional respiratory support techniques(28 days)
- Number of patients with abnormal lung CT(90 days, 1 year)
研究者
Chen Wang
professor
China-Japan Friendship Hospital