A Realworld Study of Acute Respiratory Distress Syndrome in China
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Respiratory Distress Syndrome
- Sponsor
- China-Japan Friendship Hospital
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Mortality
- Last Updated
- 9 years ago
Overview
Brief Summary
ARDS is a critical respiratory disease caused by endogenous and exogenous factors. The mortality of ARDS varies from 30 to 70%. In 2012, a new international diagnostic criterion has been put forward. Yet, its feasibility, reliability and validity need to be tested. Meanwhile, the correlation of different severity and prognosis remains unclear. As so far, the epidemiological information about ARDS in China is lacking.
Investigators plan to conduct a multi-center observational study（real-life study） to investigate the risk factors, morbidity, management and prognosis of ARDS in China, in order to facilitate standardization of diagnosis and management of ARDS and provide basic data and idea for further clinical intervention studies.
Investigators
Chen Wang
professor
China-Japan Friendship Hospital
Eligibility Criteria
Inclusion Criteria
- •≥18 years of age; hospitalized patients with main diagnosis as ARDS.
Exclusion Criteria
- •\<18 years of age
- •Patients or their families refused to participate in the study
- •Patients diagnosed as COPD, pulmonary fibrosis or bronchiectasis
Outcomes
Primary Outcomes
Mortality
Time Frame: 28days
the 28days mortality after the diagnosis of ARDS
Secondary Outcomes
- Incidence of ARDS(2 years)
- Number of patients with high risk factors(1 week)
- Length of ICU stay(90 days)
- Ventilation free days(28 days)
- Number of patients using adjuvant drugs(28 days)
- Number of patients with impaired lung function(90 days, 1 year)
- Severity of patients(2 years)
- Number of patients with conventional respiratory support techniques(28 days)
- Adverse events related to treatment(90 days)
- Number of patients with unconventional respiratory support techniques(28 days)
- Number of patients with abnormal lung CT(90 days, 1 year)