Effect of respiratory muscle training on functional capacity, breathing difficulty & heart function in people with chronic obstructive pulmonary disease
- Conditions
- Chronic obstructive pulmonary disease, unspecified,
- Registration Number
- CTRI/2023/08/056978
- Lead Sponsor
- IndianSpinal Injuries Centre- Institute of Rehabilitation Sciences
- Brief Summary
This study is a randomized, double-blind, parallel group, single-centre trial to determine the effect of inspiratory muscle training on exercise capacity, dyspnea and cardiac autonomic function in individuals with COPD. The recruited subjects will be randomized in two-groups: group-A (experimental group) and group-B (control group). Group-A will be given inspiratory muscle training and pulmonary rehabilitation and group-B will be given sham training and pulmonary rehabilitation, three times a week for eight weeks. The primary outcome is exercise capacity, will be measured with six-minute walk distance, secondary outcomes are dyspnea and cardiac autonomic function will be measured with rate of perceived exertion and heart rate variability respectively. The outcomes will be assessed at time points T0 (at the time of allotment) and T1 (after the training).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Male
- Target Recruitment
- 36
GOLD classification of COPD: moderate to severe Inspiratory muscle weakness ( PI max< 70 cm H2O).
Subjects on mechanical ventilators, Subjects with acute myocardial infarction within 3 months before inclusion, Diagnosed history of unstable angina and unstable ventricular arrhythmia within the last 3 months prior to initiation, Subjects with acute respiratory disease other than COPD, rheumatoid disease, and degenerative disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Exercise capacity will be assessed by six-minute walk distance calculated measured by six-minute walk test Six-minute walk distance will be measured at baselines and after 8 weeks of intervention.
- Secondary Outcome Measures
Name Time Method Dyspnea will be assessed by baseline & transition dyspnea index scale & Cardiac autonomic function will be assessed by heart rate variability Secondary outcomes will be assessed at the baseline before allotment & at the end of 8 weeks of intervention training
Trial Locations
- Locations (1)
National Institute of Tuberculosis and Respiratory Diseases (NITRD)
🇮🇳West, DELHI, India
National Institute of Tuberculosis and Respiratory Diseases (NITRD)🇮🇳West, DELHI, IndiaShikha SharmaPrincipal investigator956011559530shikhasharma.ss@gmail.com