Comparison of efficacy between nefopam and placebo for prevention of shivering during spinal anesthesia in patient undergoing cesarean sectio

Phase 4

• Conditions: Comparison of efficacy between Nefopam andPlacebo for prevention of shivering during spinalanesthesia in patient undergoing cesarean section; nefopam shivering prevention spinal anesthesia ceasarean section

• Registration Number: TCTR20181016002
• Lead Sponsor: Research affairs Faculty of medicine,Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-16
• Study Completion: 2019-09-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 160

Inclusion Criteria

pregnant woman gestrational age 36-42 weeks who undergoing cesarean section under spinal anesthesia
the american society of anesthesiologists physical status II-III

Exclusion Criteria

-patients who have abnormal function of thyroid, heart, lungs, neurological function
-patients who have muscle disease or history of malignant hyperthermia
-patients who have phychological problems
-patients who have a fever perioperative(body temperature more than 37.5C)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Shivering 1 hr Shivering score

Secondary Outcome Measures

Name	Time	Method
comparison of Hemodynamic between nefopam group and placebo group 6, 12, 18 and 24 hr Heart rate, Blood pressure,complication of nefopam 6, 12, 18 and 24 hr nausea, pain on injection, respiratory depression