CTRI/2020/06/026077
Completed
未知
Effect of Intraoperative Dexmedetomidine infusion on Postopearative Cognitive Dysfunction and Recovery Quality in an Elderly Patient posted for Spine Surgery: a Randomized Prospective Double Blinded Study
Indraprastha Apollo Hospital New Delhi0 sites60 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: O- Medical and Surgical
- Sponsor
- Indraprastha Apollo Hospital New Delhi
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with American Society of Anesthesiologists (ASA) physical status I\-III aged 60\- 80 years old, undergoing elective lumbar spine surgery
Exclusion Criteria
- •1\.Patients age less than 60 years and more than 80 years old.
- •2\.Patients with a pre\-operative or intraoperative ECG (electrocardiogram) that showed severe bradycardia (sinus rhythm, heart rate less than 50/ min) or conduction block
- •3\.Patients with associated renal, hepatic and respiratory dysfunction.
- •4\.Patients with history of central nervous system disease such as head injury, stroke, previous neurosurgery, behavioral disturbances or mental retardation.
- •5\.Patients with preoperative cognitive dysfunction (MMSE \<24\)
- •6\.Patients on β\-blockers, cimetidine, digoxin, α2\-agonists, anticonvulsants or psychotropic medications
- •7\.Patients with allergy to dexmedetomidine or another alpha\-2 adrenergic receptor agonist
Outcomes
Primary Outcomes
Not specified
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