Oral bisphosphonate, alendronate, for the treatment of acute Charcot neuroarthropathy in diabetic patients

Phase 4

Completed

• Conditions: Topic: Diabetes Research Network; Subtopic: Both; Disease: Diabetic foot; Nutritional, Metabolic, Endocrine; Charcot neuroarthopathy

• Registration Number: ISRCTN86625608
• Lead Sponsor: Tameside Hospital NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07-30
• Last Update Posted: 22 May 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

1. Type 1 or type 2 diabetes
2. Aged 18 - 85 years
3. Diabetic neuropathy
4. Active Charcot arthropathy

Exclusion Criteria

1. Peripheral vascular disease
2. Renal failure
3. Foot ulceration or celluitis or osteomyelitis
4. Previous amputation (more than midfoot)
5. Contraindication to study drug
6. Oesophageal or gastric problems (achalasia, ulcers)
7. Pregnancy
8. Breastfeeding
9. Risk factors for jaw osteonecrosis

Study & Design

• Study Type: Interventional
• Study Design: Not specified