Echocardiography During Ajmaline Test
- Conditions
- Brugada Syndrome
- Interventions
- Registration Number
- NCT03491475
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Brief Summary
In this study the investigators analyse echocardiographic images before and during Ajmaline test. The purpose is to know if any echocardiographic modifications are present during either negative or positive Ajmaline testing.
- Detailed Description
The diagnosis of Brugada Syndrome is made when a type 1 pattern is present on the electrocardiogram (ECG), either spontaneously or after administration of a sodium channel blocker. For pathofysiological understanding, the investigators will analyse echocardiography images before and during the administration of Ajmaline. Comparing echocardiographies before and during negative Ajmaline test, will allow the investigators to indentify the effect of Ajmaline administration on cardiac function. The comparison between images of negative and positive Ajmaline tests will expose differences related to the occurence of a type 1 ECG.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- >17 years old
- clinical indication for Ajmaline test
- History of right ventricular outflow tract ablation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Positive Ajmaline test Ajmaline test Appearance of a type 1 ECG during Ajmaline test Negative Ajmaline test Ajmaline test No appearance of a type 1 ECG during Ajmaline test
- Primary Outcome Measures
Name Time Method Speckle tracking strain measurement 1 day at the time of enrollment Cardiac function assessed by speckle tracking peak strain and peak strain dispersion
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UZ Brussel
🇧🇪Jette, Brussels, Belgium