ISRCTN13396702已完成不适用
Effects of Annurca apple polyphenolic extract on intestinal cholesterol solubility in healthy subjects: A monocentric, double-blind, randomised, placebo-controlled, cross-over study
Samnium Medical Cooperative0 个研究点目标入组 50 人开始时间: 2017年11月9日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Men and women between 18-83 years of age, of white race, with the following range values of serum cholesterol parameters at baseline (week 0):
- •1. TC, 200-260 mg/dL
- •2. HDL-C, 30-45 mg/dL
- •3. LDL-C, 189-206 mg/dL
- •4. TG, 170-280 mg/dL
- •5. Body mass index (BMI) between 18 and 30 kg/m2
排除标准
- •Healthy adults (males and females) with:
- •1. Smoking
- •2. Obesity (BMI >30 kg/m2)
- •3. Diabetes
- •4. Hepatic disease
- •5. Renal disease
- •6. Heart disease
- •7. Family history of chronic diseases
- •8. Drug therapy or supplement intake for hypercholesterolemia
- •9. Drug therapy or supplement intake containing apple polyphenols
- •10. Heavy physical exercise (>10 h/week)
- •11. Pregnant women, women suspected of being pregnant, women who hoped to become pregnant, breastfeeding
- •12. Birch pollen allergy
- •13. Use of vitamin/mineral supplements 2 weeks prior to entry into the study
- •14. Donation of blood less than 3 months before the study
研究者
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