Evaluation of Annurca apple polyphenols on cholesterol metabolism in mildly hypercholesterolemic healthy subjects: a monocentric, randomised, cross-over, placebo-controlled 4 weeks study

Hospital AO Rummo0 个研究点目标入组 500 人开始时间: 2015年11月18日最近更新: 2016年10月17日

适应症

试验速览

暂无简介。

•Men and women between 18-83 years of age, of white race, with the following range values of serum cholesterol parameters at baseline (week 0):
•1. TC, 200-260 mg/dL
•2. HDL-C, 31-45 mg/dL
•3. LDL-C, 190-205 mg/dL.
•4. Body mass index (BMI) between 18 and 30 kg/m2

•Healthy adults (males and females) with:
•1. Smoking
•2. Obesity (BMI >30 kg/m2)
•3. Diabetes
•4. Hepatic disease
•5. Renal disease
•6. Heart disease
•7. Family history of chronic diseases
•8. Drug therapy or supplement intake for hypercholesterolemia
•9. Drug therapy or supplement intake containing apple polyphenols
•10. Heavy physical exercise (>10 h/week)
•11. Pregnant women, women suspected of being pregnant, women who hoped to become pregnant, breastfeeding
•12.Birch pollen allergy
•13.Use of vitamin/mineral supplements 2 weeks prior to entry into the study
•14.Donation of blood less than 3 months before the study

发起方

Hospital AO Rummo