REBIRTH active school - effects of a school-based mobility program on sustained health benefits for pupils.
Recruiting
- Conditions
- Cardiovascular morbidity
- Registration Number
- DRKS00012371
- Lead Sponsor
- Klinik für Herz-, Thorax-, Transplantations- und Gefäßchirurgie (HTTG)Medizinische Hochschule Hannover
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Second and fifth grade pupils, whose schools participates in the Rebirth active School mobility program.
Exclusion Criteria
None
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Telomere length of DNA from peripheral mononuclear cells (measured by PCR (polymerase chain reaction)) at inclusion, after 1 year and after 2 years.
- Secondary Outcome Measures
Name Time Method The followig prameters will be analyzed as secondary endpoints at inclusion, after 1year, and after 2 years:<br>Pulse wave velocity will be measured oscillometrically by using the Vicorder device, which is validated for pediatric use.<br>Intima-media thickness will be measured by ultrasound, employing the guidelines of the Mannheim Consensus.<br>p16INK4a-Expression will be determined by RT-PCR in peripheral mononuclear cells.