BOOST: A new pathway with BronchOscopic or Oesophageal ultrasound for lung cancer diagnosis and STaging

Not Applicable

Completed

• Conditions: ung cancer; Cancer; Lung cancer

• Registration Number: ISRCTN49573946
• Lead Sponsor: niversity College London Hospitals NHS Foundation Trust (UK)

Brief Summary

2015 Results article in https://www.ncbi.nlm.nih.gov/pubmed/25660225 results (added 10/09/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-05-23
• Study Completion: 2011-10-01
• Last Update Posted: 7 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 133

Inclusion Criteria

1. Aged greater than 18 years, either sex
2. Consecutive patients suspected of lung cancer on CT scan
3. Written informed consent
4. Able to tolerate fibre-optic bronchoscopy

Exclusion Criteria

1. Evidence of severe or uncontrolled systemic disease that makes it undesirable for the patient to participate in the trial
2. Any disorder making reliable informed consent impossible
3. Patient unlikely to tolerate bronchoscopy
4. Patients with extra-thoracic disease, supraclavicular lymphadenopathy or pleural effusion

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Time from first outpatient appointment to decision to treat.<br><br> Information for the endpoints will be collected prospectively as patients go through the diagnostic and staging process and case report forms (CRFs) will be updated weekly. The information will be obtained from multi-disciplinary team meetings (MDTs), patient notes and electronic patient records.<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. The health care costs of diagnosing and staging lung cancer<br> 2. The number of tests and outpatient visits a patient requires to be diagnosed and staged with lung cancer<br> 3. The proportion of lung cancer patients that are diagnosed and staged with a single test after CT scan<br> 4. The time from first outpatient appointment to treatment<br> 5. The number of futile thoracotomies<br><br> Information for the endpoints will be collected prospectively as patients go through the diagnostic and staging process and case report forms (CRFs) will be updated weekly. The information will be obtained from multi-disciplinary team meetings (MDTs), patient notes and electronic patient records.<br>