The impact of preinduction fentanyl dosing strategy on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A concept evaluation of equi-dose fentanyl given as a single-bolus or divided intermittent boluses or continuous infusion administration technique.
- Conditions
- Post operative nausea & vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.Keywords- Post operative nausea & vomiting (PONV) , laparoscopic cholecystectomyTrefwoorden-Post-operatieve misselijkheid en braken (PONV), laparoscopische cholecystectomie
- Registration Number
- NL-OMON21891
- Lead Sponsor
- Department of Anaesthesiology, Pain and Perioperative Medicine. Sir Ganga Ram Hospital, Old Rajinder Nagar ,New Delhi-110060 .India
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 270
Inclusion Criteria
1. Male or female gender;
2. Aged 20-60 years age;
Exclusion Criteria
1. Patients with uncompensated systemic co-morbidity [cardiac (hypertension, coronary artery disease, cardiomyopathy, arrhythmias), respiratory (bronchial asthma, COPD), endocrinology (diabetes mellitus, thyroid disease), hepato-renal, CNS];
2. Allergy to opioid drugs;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The impact of pre-induction IV fentanyl dosing methodology on reduction of PONV incidence;<br /><br>2. Reduction in the use of postoperative antiemetics.
- Secondary Outcome Measures
Name Time Method The effect of different methods of pre-induction intravenous fentanyl administration method on patient response profile including:<br /><br>1. Hemodynamics: Heart rate (HR), noninvasive blood pressure (NIBP);<br /><br>2. Respiration: Respiratory rate (RR), depth of breathing, oxygen saturation (SpO2);<br /><br>3. Central nervous system: Orientation, consciousness (level of sedation), bispectral index (BIS).