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Clinical Trials/NCT05129397
NCT05129397
Completed
N/A

A Randomized Controlled Trial to Improve Biobehavioral Regulation Among High-Adversity Mothers and Young Children

Tulane University1 site in 1 country44 target enrollmentNovember 1, 2021
ConditionsPsychopathology

Overview

Phase
N/A
Intervention
Not specified
Conditions
Psychopathology
Sponsor
Tulane University
Enrollment
44
Locations
1
Primary Endpoint
Change from baseline maternal depressive symptoms at post-intervention
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study is a randomized controlled confirmatory efficacy trial of virtual Mom Power (MP), a group-based, relationship-focused multifamily preventive intervention.

Detailed Description

This study is a randomized controlled confirmatory efficacy trial of virtual Mom Power (MP), a group-based, relationship-focused multifamily intervention with previously demonstrated effectiveness improving maternal mental health and parenting stress in randomized controlled trials. vMP targets 5 core components: 1) enhancing social support; 2) attachment-based parenting education; 3) self-care, including affect regulation; 4) guided parent-child interactions, and 5) connecting to care. Eligible and enrolled participants will be randomized to receive the 10 week group-based intervention or 10 weeks of informational mailings; both groups will receive individual home-based sessions. Outcomes include maternal social support, psychopathology, sensitive parenting, child psychopathology, two-generational biobehavioral self-regulation targets (Respiratory Sinus Arrhythmia), parent and child emotion and behavior regulation, and dyadic behavioral and physiological synchrony. Assessments will occur at intake, post, and 6 months following the group.

Registry
clinicaltrials.gov
Start Date
November 1, 2021
End Date
January 30, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sarah Gray

Associate Professor of Psychology, Clinical Professor of Psychiatry & Behavioral Sciences, Principal Investigator

Tulane University

Eligibility Criteria

Inclusion Criteria

  • Enrollment status in one of the following services: Supplemental Nutrition Assistance Program (SNAP), Family Independence Temporary Assistance Program (FITAP), Medicaid, Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), or Head Start
  • Maternal age of at least 18 years
  • Mother is primary caregiver of child
  • Mother speaks English
  • Child age is between 3-5 years
  • Family resides within 8 parish New Orleans metro area

Exclusion Criteria

  • Mother is not biological mother
  • Diagnosis of a heart condition in the mother or the child
  • Presence of a pacemaker in the mother or the child
  • Child diagnosis of autism or global developmental delay
  • Active maternal substance use
  • Active maternal psychosis

Outcomes

Primary Outcomes

Change from baseline maternal depressive symptoms at post-intervention

Time Frame: At completion of intervention, approximately 3 months

Mothers will report on their own depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9) at baseline, post-intervention, and 6 month follow up; change in sum scale from baseline at post-intervention will be assessed. Higher scores reflect more depressive symptoms.

Change from baseline child behavior at post-intervention

Time Frame: At completion of intervention, approximately 3 months

Mothers will report on child behavior on the Child Behavior Checklist (CBCL 1.5-5). Sum scores will be used. Higher scores reflect more behavior problems.

Change from baseline maternal depressive symptoms at 6 month follow up

Time Frame: 6 months (follow up)

Mothers will report on their own depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9) at baseline, post-intervention, and 6 month follow up; change in sum scale from baseline to 6 month follow up will be assessed. Higher scores reflect more depressive symptoms.

Change from baseline maternal posttraumatic stress symptoms at post-intervention

Time Frame: At completion of intervention, approximately 3 months

Mothers will report on their own posttraumatic stress symptoms using the Posttraumatic Checklist for Diagnostic and Statistical Manual Diploma in Social Medicine-5 (PCL-5). Sum scales will be assessed at baseline, post-intervention (3 months), and 6 month follow up; change in sum scale from baseline to 3 month follow up will be assessed. Higher scores reflect more posttraumatic stress symptoms.

Change from baseline maternal posttraumatic stress symptoms at 6 month follow up

Time Frame: 6 months (follow up)

Mothers will report on their own posttraumatic stress symptoms using the Posttraumatic Checklist for Diagnostic and Statistical Manual Diploma in Social Medicine-5 (PCL-5). Sum scales will be assessed at baseline, post-intervention (3 months), and 6 month follow up; change in sum scale from baseline to 6 month follow up will be assessed. Higher scores reflect more posttraumatic stress symptoms.

Change from baseline child behavior at 6 month follow up.

Time Frame: 6 months (follow up)

Mothers will report on child behavior on the Child Behavior Checklist (CBCL 1.5-5). Sum scores will be used. Higher scores reflect more behavior problems.

Secondary Outcomes

  • Change in parenting stress from baseline to 6 month follow up(6 months)
  • Change in parenting stress from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in self-report parent child relationship from baseline to follow up(6 months)
  • Change in maternal social support from baseline to post intervention(At completion of intervention, approximately 3 months)
  • Change in Working Models from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in maternal emotion regulation from baseline to follow up(6 months)
  • Change in self-report parent child relationship from baseline to post intervention(At completion of intervention, approximately 3 months)
  • Change in observed parenting sensitivity from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in maternal social support from baseline to follow up(6 months)
  • Change in maternal emotion regulation from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in child Respiratory Sinus Arrhythmia reactivity from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in maternal emotion regulation while parenting from baseline to post intervention(At completion of intervention, approximately 3 months)
  • Change in maternal emotion regulation while parenting from baseline to follow up(6 months)
  • Change in maternal resting Respiratory Sinus Arrhythmia from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in maternal Respiratory Sinus Arrhythmia reactivity from baseline to post-intervention(At completion of intervention, approximately 3 months)
  • Change in child resting Respiratory Sinus Arrhythmia from baseline to post-intervention(At completion of intervention, approximately 3 months)

Study Sites (1)

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